Certain functional foods or bioactive ingredients with anti-fatigue properties help reduce fatigue and increase overall energy levels. Aprofood has a well-established scientific and technical system, along with a team of experts, to support the evaluation of your product's effectiveness in anti-fatigue.
The mechanisms of action of anti-fatigue interventions involve complex interactions at the molecular, cellular, and systemic levels, which vary depending on the specific ingredient; some of the mechanisms are as follows.
Facilitating cellular energy production by aiding in metabolic processes, such as ATP synthesis in mitochondria, to support mitochondrial function and potentially reduce fatigue.
For example, adaptogens, including ginseng, rhodiola, and ashwagandha can help regulate the body's stress response, reducing the impact of chronic stress on fatigue.
Influencing neurotransmitter levels, improving alertness and reducing perceived fatigue. For example, caffeine can reduce perceived fatigue by blocking adenosine receptors in the brain. This leads to increased release of neurotransmitters like dopamine and norepinephrine.
Polyphenols and omega-3 fatty acids can potentially alleviate fatigue by reducing inflammation, which is associated with various fatigue-related conditions.
Amino acids, such as branched-chain amino acids (BCAAs) and glutamine, can aid in muscle repair and reduce muscle-related fatigue after exercise.
By providing comprehensive and scientifically rigorous methodologies that combine in vitro and in vivo testing, Aprofood helps evaluate the anti-fatigue properties of bioactive compounds or functional foods.
Biochemical Analysis
In-depth studies of the intricate biochemical markers associated with fatigue, elucidating the molecular-level influence of functional food ingredients.
Customized Research Proposal
Tailoring individualized research plans to align with clients' distinct requirements, ensuring meticulous data acquisition.
Molecular Pathway Mapping
Identifying and charting distinct molecular pathways influenced by functional food ingredients, providing strategic guides for precision fatigue management.
Physiological Assessment
Conducting evaluations of physiological parameters, including endurance, energy metabolism, and stress response to quantify the comprehensive anti-fatigue efficacy.
Target Confirmation. Understand the specific aspects that you want to investigate.
Experimental Design. Based on the properties of the ingredient and your desired objectives, we will provide a well-designed experiment, including both in vivo and in vitro assays.
Data Analysis. The data were systematically analyzed to assess the significance of differences, and the results were visually presented.
Report Generation. Provide a clear, accurate and scientifically rigorous report, including study design, methodology and interpretation of results.
Cell Culture Models. Choose appropriate cell lines that represent fatigue-related processes, such as muscle cells or cells related to energy metabolism.
Treatment. Expose the cultured cells to varying concentrations of the bioactive ingredient.
Measure Indicators. Including cell viability, proliferation, metabolic activity, energy metabolism, oxidative stress markers, and muscle-related parameters.
Animal Experiment Design. Consider fatigue models and design dose and experimental group.
Exercise Performance. Assess exercise performance through swimming tests or other protocols. Measure parameters like endurance, fatigue onset, and recovery.
Biomarker Analysis. Analyze blood samples for markers of fatigue, such as lactate levels, creatine kinase, and cytokines related to inflammation and muscle damage.
Adaptogenic Properties
Studying the adaptogenic capabilities of functional food ingredients for modulating the body's stress and fatigue response.
Mitochondrial Function
Evaluating the influence of ingredients on mitochondrial function—an essential factor in cellular energy production and fatigue resistance.
Neurotransmitter Modulation
Investigating the modulation of neurotransmitter systems by ingredients to improve cognitive function and diminish mental fatigue.
Anti-Inflammatory Effects
Exploring the anti-inflammatory attributes of functional food ingredients, targeting fatigue associated with inflammation.
As an expert in the field of the food industry, Aprofood specializes in food ingredient supply as well as contract development of new ingredients. No matter what size of your business and where you're located, we'd like to work with you. Please feel free to contact us.
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