Synbiotics Development Service

Synbiotics Development Service

Synbiotic is defined as "a mixture comprising live microorganisms and substrate(s) selectively utilized by host microorganisms that confers a health benefit on the host", this combination approach is considered more likely to improve gut health and overall well-being than using prebiotics or probiotics alone. Aprofood is constantly engaged in basic scientific research and can provide you with synbiotics development services.

Complementary Symbiotics

Typically, almost all commercially available synbiotics are complementary symbiotics, which are designed by combining more than one probiotic plus prebiotic for synergistic health benefits, and the probiotic and prebiotic components of the formula must meet their respective definitions and criteria. Functional foods containing synbiotics can be in various forms, including yogurt, fermented foods, and specialized supplements.

Fig 1. Probiotics, prebiotics, and adjacent fields.Fig 1. Probiotics, prebiotics, and adjacent fields. (Cunningham M, et al., 2021)

Synergistic Synbiotics

Recently, researchers are working on developing the synergistic synbiotic, which is a type of envisioned symbiotic and it is formulated using live microorganisms and selectively utilized substrates, neither of which needs to meet the definition of probiotics or prebiotics, but the live microorganisms are chosen depending on their ability to provide health benefits and the selected substrates need to support the growth and activity of the co-administered microorganisms.

Fig 2. The difference between complementary and synergistic synbiotics.
Fig 2. The difference between complementary and synergistic synbiotics. (Swanson K S, et al., 2020)

Our Service

Aprofood has been committed to basic scientific research, taking into account applicable efficacy, mechanistic evidence and safety factors, to provide you with development services for synbiotic.

Process of Synbiotics Development

Selection of Prebiotic

Select prebiotic compounds that a beneficial to gut health and are compatible with the selected probiotic strains.

Selection of Probiotic

Probiotic strains are selected based on their stability, viability, safety, function and ability to interact positively with the selected prebiotics.

Compatibility Testing

Evaluate parameters such as survival rates, growth, and metabolic activity of the probiotic strains in the presence of prebiotics, which aims to ensure that prebiotics and probiotics can coexist within the formulation.

Formulation Design

Design the synbiotic formulation by combining the selected prebiotics and probiotics in appropriate ratios and concentrations. Depending on the desired application, we can design different delivery formats (e.g., capsules, powders, beverages).


Assessing the compatibility with food matrices, stability under processing conditions and potential health benefits.

Developing a mature food synbiotics product requires characterization of its safety and performance, verification of its bioactive function, as well as investigation of its formulation techniques for food application and its compatibility with food matrices. Here you can get a one-stop service for product development.

Why Choose Us?

Fig 3. Wide Range of Ingredients.

Wide Range of Ingredients

We are a one-stop shop for all types of food ingredients.

Fig 4. Customized Formulation Portfolio.

Innovative Program

We have a systematic development program to meet innovation needs.

Fig 5. Innovative Program.

Customized Formulation Portfolio

We develop customized additive combinations to optimize value for all types of foods and beverages.

Fig 6. Quality Assurance.

Quality Assurance

We have the highest standards of production and quality testing procedures.

Aprofood is a reliable partner for you, we provide you with high-quality food ingredients and help you find the optimal solution for food development and innovation. Our product and service comply with global, regional, and local regulations. Please contact us for more information on developing your business.


  1. Cunningham, M.; et al. Shaping the Future of Probiotics and Prebiotics. Trends in Microbiology. 2021, 29(8): 667-685.
  2. Swanson, K.S.; et al. The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics. Nat Rev Gastroenterol Hepatol. 2020, (17):687–701.
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